Document Details

Document Type : Thesis 
Document Title :
VITAMIN D STATUS AND AUTOIMMUNE DISEASE (HASHIMOTO’S THYROIDITIS) IN SAUDI ARABIAN WOMEN
مستوى فيتامين د ومرض المناعة الذاتي (التهاب الغدة الدرقية الهاشيموتو) بين نساء المملكة العربية السعودية
 
Subject : Faculty of Home Economics 
Document Language : Arabic 
Abstract : Vitamin D Status and Autoimmune Disease (Hashimoto’s Thyroiditis) in Saudi Arabian Women By Bayan Abdulhafid Aljahdali Supervised By Dr. Fatimah Mohammad Ali Yousef Abstract Recently, the role of vitamin D on auto¬immune disorders has been investigated by several researchers. Hashimoto’s thyroiditis (HT) chronic inflammation is one of auto¬immune disorders, caused by environmental and genetic factors that may leads to produce antibodies from immune system that attacked thyroid gland, however; causes are not yet completely understood. Objective: To examine the 25 hydroxy vitamin D (25(OH) D3) status in Saudi Arabian females with HT Saudi female. Subjects and Methods: A cross-sectional study was recruited 50 female patients diagnosed by HT aged 20 and above, from King Abdulaziz University Hospital in Jeddah, Saudi Arabia. Patients were on specific routine of LT4 medication for a minimum 6 months. Blood samples were collected to measure the levels of 25(OH) D3, thyroid stimulation hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4) and calcium. Results: Biochemical data revealed that mean values for vitamin D among the three vitamin D categories were significant (P<0.05). There was insignificant relationship between vitamin D and TSH, as well as between vitamin D and FT3 (r=0.147, r=0.148, P>0.05) respectively. In addition, there was insignificant negative correlation between calcium level and TSH, and FT3 (r= -0.121, r=-0.264, P>0.05), respectively. Although there was a significant relationship between BMI categories and vitamin D levels, the study observed that majority of obese patients had high percentage of vitamin D deficiency. Conclusion: There was no association between 25(OH) D levels and HT among Saudi Arabian women. However, significant difference was found between vitamin D status in patients have insufficient and sufficient level (P < 0.05). 
Supervisor : Dr. Fatimah Mohammad Ali Yousef 
Thesis Type : Master Thesis 
Publishing Year : 1439 AH
2018 AD 
Added Date : Wednesday, March 21, 2018 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
بيان عبد الحفيظ الجحدليAljahdali, Bayan AbdulhafidResearcherMaster 

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