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نوع الوثيقة |
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مقال في مجلة دورية |
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عنوان الوثيقة |
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POTENTIATING TOXICOLOGICAL INTERACTION OF SINGLE-WALLED CARBON NANOTUBES WITH DISSOLVED METALS POTENTIATING TOXICOLOGICAL INTERACTION OF SINGLE-WALLED CARBON NANOTUBES WITH DISSOLVED METALS |
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لغة الوثيقة |
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الانجليزية |
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المستخلص |
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The present study explored the ecotoxicology of single-walled carbon nanotubes (SWCNTs) and their likely interaction with dissolved metals, with a focus on the effect of in vivo exposure in marine mussels. Any nano-scale effects were negated by the tendency of uncoated SWCNTs to agglomerate in water, particularly with high ionic strength as is the case in estuarine and full-strength seawater. However, SWCNTs, in combination with natural organic matter, remained suspended in seawater for long enough to become available to filter-feeding mussels, leading to their concentration on and increased contact with gill epithelia during exposure. For the first time, the authors describe a potentiating toxicological effect, expressed as DNA strand breaks obtained using the comet assay, on divalent metals afforded by negatively charged SWCNT agglomerates in seawater at concentrations as low as 5 mu gL(-1). This is supported by the observation that SWCNTs alone were only toxic at concentrations 100 mu gL(-1) and that the SWCNT-induced DNA damage was correlated with oxidative stress only in the absence of metals. If these laboratory experiments are confirmed in the natural environment, the present results will have implications for the understanding of the role of carbon nanotubes in environmental metal dynamics, toxicology, and consequently, regulatory requirements. |
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ردمد |
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0730-7268 |
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اسم الدورية |
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ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY |
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المجلد |
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32 |
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العدد |
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12 |
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سنة النشر |
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1434 هـ
2013 م |
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نوع المقالة |
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مقالة علمية |
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تاريخ الاضافة على الموقع |
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Tuesday, July 18, 2017 |
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الباحثون
| Majed (Al-Shaeri | (Al-Shaeri, Majed | باحث | | |
| Dina Ahmed | Ahmed, Dina | باحث | | |
| Fiona McCluskey | McCluskey, Fiona | باحث | | |
| Gavin Turner | Turner, Gavin | باحث | | |
| Lynn Paterson | Paterson, Lynn | باحث | | |
| Elisabeth Dyrynda | Dyrynda, Elisabeth | باحث | | |
| Mark Hartl | Hartl, Mark | باحث | | |
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