تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Nutrigenomics, Inflammaging, and Osteoarthritis
Nutrigenomics, Inflammaging, and Osteoarthritis
 
لغة الوثيقة : الانجليزية 
المستخلص : Osteoarthritis (OA) is a painful condition affecting over 40% of people aged over 65 years old. It has been established that it involves considerable local inflammation and, as such, is the classic example of inflammaging; a condition for which age-related inflammation is a contributing factor. Nutrigenomics is the study of the effects of foods and food constituents on gene expression and is becoming of great interest to both patients with OA as well as and clinicians and scientists interested in development of novel therapies for OA. One strong motivation behind this avenue of research is the fact that there are no proven effective treatments that can arrest or reverse OA. Inflammaging in relation to the OA joint is a complex topic involving cytokines and reactive oxygen species. This review discusses these together with the contribution of loss of muscle function to the progression of OA. This review the latest literature on nutraceuticals regarded as offering the best therapeutic potential. These include resveratrol from red wine grapes and epigallocatechin gallate (EGCG) from green tea. It is too early to provide definitive answers as to their effectiveness, but there is clearly sufficient data to warrant further investigation. 
ردمد : 1118930452 
اسم الدورية : Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods, Second Edition 
المجلد : 1 
العدد : 1 
سنة النشر : 1436 هـ
2015 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Monday, April 25, 2016 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
Ali MobasheriMobasheri, Ali باحث رئيسي  
Richard Barrett-JolleyBarrett-Jolley, Richard باحث مشارك  
Caroline A. StauntonStaunton, Caroline A.باحث مشارك  
Chris FordFord, Chris باحث مشارك  
Yves HenrotinHenrotin, Yves باحث مشارك  

الملفات

اسم الملفالنوعالوصف
 40797.pdf pdf 

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